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Wolpert's Principles of Development (7th edition)

Author: 
Cheryll Tickle, Alfonso Martinez Arias, Marysia Placzek, and Lewis Wolpert
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Wolpert's Principles of Development, the latest edition of the prize-winning textbook, opens up the fascinating field of developmental biology to undergraduates studying biology, medicine, and veterinary science. By focusing on the underlying processes shared by diverse organisms, the textbook lays the foundation for a deep understanding.

Key Features:

  • An emphasis throughout is on the underlying principles - which underpin not only the development of the body and its different parts but also the commonalities between the development of different organisms - and this enables students to get a clear sense of the 'big picture' of the subject.
  • Custom-drawn artwork and integrated animations and videos help to make the visualisation of processes and mechanisms in this challenging subject as straightforward as possible.
  • Medical Boxes explore key developmental diseases and explain how developmental biology furthers our understanding of human health and disease. Further experimental detail, including Experimental Boxes, from both classic and current research, demonstrates 'how we know what we know'
  • Also available as an e-book with enhanced learning objectives, self-assessment interactive quizzes and multi-media content to offer a fully immersive experience and extra learning support.

New to this Edition:

  • Chapter 7 is a new chapter on Embryonic stem cells, embryo models, and regenerative medicine, to ensure the book's coverage stays up to date with this very active area of research in developmental biology.
  • Chapters 3 and 4 on vertebrate development have been restructured and updated, especially coverage of mouse development, to ensure major concepts and principles are explained with recent supporting experimental evidence.
  • Chapter 10 on the nervous system has been completely revised and updated, with more emphasis on neural tube patterning.
  • Chapter 14, which covers nematodes and sea urchins, has been made online as part of the ebook.
  • There are more examples of the use of CRISPR to address problems like sickle cell disease (Ch6), and evolution of limbs from fins (Ch13).
  • Examples of single-cell RNA sequencing can be found throughout the book (Ch3, Ch6, Ch7, Ch10, Ch11, Ch12).
  • Smaller revisions, updates, and new figures have been included throughout.
Index: 

1:History and basic concepts
2:Development of the Drosophila body plan
3:Vertebrate development I: Establishing the body plan
4:Vertebrate development II: completing the body plan
5:Morphogenesis: change in form in the early embryo
6:Cell differentiation and stem cells
7:Embryonic stem cells, embryo models, and regenerative medicine
8:Germ cells, fertilization, and sex determination
9:Organogenesis
10:Development of the nervous system
11:Growth, post-embryonic development, and regeneration
12:Plant development
13:Evolution and development

About the author: 

Cheryll Tickle, Emeritus Professor, University of Bath, Alfonso Martinez Arias, ICREA Research Professor, Universidad Pompeu Fabra, Barcelona, Marysia Placzek, Professor of Developmental Neurobiology, University of Sheffield, and Lewis Wolpert, Late Emeritus Professor of Biology, University College London

Contributors:
Mary Baylies, Professor, Weill Graduate School of Medical Sciences, Cornell University
James Locke, Sainsbury Laboratory, University of Cambridge
Peter Lawrence, Emeritus Scientist, MRC Laboratory of Molecular Biology, Cambridge
Eleanor Lawrence, freelance science writer and editor
Matthew McClements, Science Illustrator

"I am incredibly thankful for this book, and wish more study books used your method of layout and explanation, as I have not seen it in any of the other course material I'e had over the past three years." - Larissa Dijks, student, Universiteit Utrecht, Netherlands

Product details

ISBN : 9780192896612

Author: 
Cheryll Tickle, Alfonso Martinez Arias, Marysia Placzek, and Lewis Wolpert
Pages
800 Pages
Format
Paperback
Size
268 x 205 mm
Pub date
Apr 2025
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Wolpert's Principles of Development (7th edition)

Wolpert's Principles of Development (7th edition)

Wolpert's Principles of Development (7th edition)