New to this Edition:
Sugars are familiar as vital sources of energy. Yet the biological importance of the sugars extends well beyond their value as cellular fuels.
Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their function at the molecular, cellular, and organismal level. Employing a two-part structure, the book leads us through essential principles and concepts upon which the discipline is grounded, before exploring the diverse roles of sugars throughout biological systems, including development, cell signalling, and protein trafficking. It also emphasises the importance of glycobiology in disease, and explains how an understanding of the link between the two is enabling us to develop new therapeutic strategies.
Taking the student from the fundamental principles to the frontiers of the subject, and with a wealth of learning features to get the most out of their studies, Introduction to Glycobiology remains the ideal resource for students and teachers alike.
Online Resource Centre
For students:
· Updates - surveys of key developments in the field, provided on a six-monthly basis, to maintain currency
· Library of 3D, rotatable molecular structures to help students visualize structures and gain a proper appreciation of the link between structure and function
· Hyperlinked references to facilitate access to primary literature
For registered adopters of the book:
· Full colour figures, available for download individually or as PowerPoint slides with key explanatory points
· Answers to end-of-chapter questions
· Journal Clubs - suggested papers and discussion questions linked to topics covered in the book
Part 1: Structures and biosynthesis of glycans
1:Concepts of glycobiology
2:N-Linked glycosylation
3:O-Linked glycosylation
4:Glycolipids and membrane protein glycosylation
5:Enzymology and cell biology of glycosylation
6:Glycomics: analysis of glycan structures
7:Conformations of oligosaccharides
Part 2: Glycans in biology
8:Effects of glycosylation on protein structure and function
9:Carbohydrate recognition in cell adhesion and signalling
10:Glycoprotein trafficking in cells and organisms
11:Glycobiology of plants, bacteria, and viruses
12:Glycobiology and development
13:Glycosylation and disease
14:The future of glycobiology
Review from previous edition
This book is an absolute must for all lecturers and students alike of glycobiology ... Wholeheartedly recommended. - Microbiology Today, November 2006
It covers the breadth of glycobiology very well and provides sufficient depth to provide a platform for further research. - Dr Gavin M. Brown, Lancaster University
Others are not written as clearly or concisely as Taylor and Drickamer. - Prof Y.C. Lee, John Hopkins University
I prefer this book highly above the other text books available. - Prof Dr J.P. Kamerling, Utrecht University
Dr Taylor and Professor Drickamer should be congratulated on writing a textbook that presents the enormous subject of glycobiology with energy and enthusiasm and doing so in a manner that should be accessible to their target audience. - Biochemist e-volution, April 2006
ISBN : 9780199569113
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