The Animal Spirit Doctrine and the Origins of Neurophysiology

ISBN : 9780199766499

Chris U. M. Smith; Eugenio Frixione; Stanley Finger; William Clower
304 ページ
225 x 282 mm

How do we become aware of things and events in the outside world, and how does the brain control the muscular system and behavior? This book examines the history of Western attempts to explain how messages might be sent from the sense organs to the brain and from the brain to the muscles. It focuses on a construct called animal spirit, which would permeate philosophy and guide physiology and medicine for over two millennia. The authors' story opens along the Eastern Mediterranean, where they examine how Pre-Socratic philosophers related the soul to air-wind or pneuma. They then trace what Hippocrates, Plato and Aristotle wrote about this pneuma, and how Stoic and Epicurean philosophers approached it. They also visit Alexandria, where Hellenistic anatomists provided new thoughts about the nerves and the ventricles. Thereafter, the authors return to the Greek mainland, where they show how Galen's pneuma psychikon or spiritus animae would provide an explanation for sensations and movements. Galen's writings would guide science and medicine for well over a thousand years, albeit with some modifications. One change, found in early Christian writers Nemesius and Augustine, involved assigning perception, cognition, and memory to different spirit-filled ventricles. After examining how pious Scholastics later dealt with the nerve spirit, the authors turn to how questions began to be raised about it in the 1500s and 1600s. Here they examine the rise of modern science with its revealing experiments, microscopic observations, and attempts to break with the past. Descartes, Swammerdam, Borelli, Glisson, Willis, Newton, Hartley, Boerhaave and Haller are among the featured players in this part of the story. Nevertheless, the animal spirit doctrine continued to survive (although modified), because no adequate replacement for it was immediately forthcoming. The replacement theory stemmed from experiments on electric fishes started in the 1750s. Additional research on these fishes and then on frogs eventually led scientists to abandon their time-honored ideas. The authors trace some of the developments leading to modern electrophysiology and end with an epilogue centered on what this history teaches us about paradigmatic changes in the life sciences.


Section 1: The Doctrine Introduced
Chapter 1: Psyche and soma
Chapter 2: Alexandria and Hellenistic psychophysiology
Section 2: The Doctrine Established
Chapter 3: Biblical anima-spirit
Chapter 4: The Islamic Ascendancy
Chapter 5: Animal spirit in an age of Faith
Section 3: The Doctrine Questioned
Chapter 6: Descartes
Chapter 7: Experiment and observation
Chapter 8: Theory and argument
Section 4: The Doctrine in Retreat
Chapter 9: Vibrations and subtle fluids
Chapter 10: Animal spirit in action
Chapter 11: Non-spiritual physiology I: " rather than Chapter 12 Non-spiritual physiology II: Irritable fibers
Section 5: The Doctrine Discarded
Chapter 13: The increasingly electrical world
Chapter 14: Electric fishes and the path to animal electricity
Chapter 15: From Fish to Frogs and nerve Electricity


Chris Smith holds degrees in Zoology, Physics and Biophysics and a PhD in Neuroscience. Since retiring as Dean of the Faculty of Life and Health Sciences at Aston in 1996 he has devoted his time to the history and philosophy of neuroscience. He has published a number of books on neuroscience and the history of biology and has edited books on cranial trepanation, Erasmus Darwin, and eighteenth-century neuroscience. He has published some 140 academic papers and chapters and has acted as section editor in neurophilosophy for the Journal of the History of the Neurosciences. ; Eugenio Frixione is a cell physiologist who has published mainly experimental basic research on several mechanisms of cell motility in neural and epithelial tissues, and in unicellular parasites. Recently he has published studies on the intellectual evolution of major concepts about cell structure and function, as well as on key advances in the understanding of muscle physiology and other instances of biological motion. ; Stanley Finger first studied recovery from brain damage and then turned to the history of the neurosciences. His monographs in the latter domain include Origins of Neuroscience (with OUP), Minds Behind the Brain (with OUP), Doctor Franklin's Medicine, and most recently (with OUP), A Shocking History of Electric Fishes. He has edited books on cranial trepanation, eighteenth-century neuroscience, and the history of neurology, has published approximately 150 papers in edited journals, and has long served and continues to serve as editor of the Journal of the History of the Neurosciences. Will Clower is trained in neurophysiology, studying the mechanisms of movement control associated with motor learning. In the process of performing his neuroscience research in France, Dr Clower wrote and later published two books on the Mediterranean dietary behaviors. He now provides wellness programming for corporations, hospitals, and wellness centers around the United States.