ISBN : 9780199681648
In this edited volume, experts on the treatment of dementia associated with Parkinson's Disease (PD) describe in detail the current status of knowledge in their respective area of expertise. The importance and clinical relevance of cognitive impairment and dementia in PD is emphasized, all relevant aspects including epidemiology, full and detailed spectrum of clinical features, current knowledge on pathology, neurochemistry and genetics, findings in auxillary investigations, relation to other neurodegenerative disorders, diagnostic process and management are described, rounded-up by discussion of future research directions and expectations. The text is complemented and enriched with tables, figures and is heavily referenced thereby capturing all relevant literature.
1. Introduction
2. Epidemiology of dementia associated with Parkinson's disease
3. General features, mode of onset and course of dementia in Parkinson's disease
4. Cognitive profile in Parkinson's disease dementia
5. Neuropsychiatric symptoms in Parkinson's disease dementia
6. Interaction between affect and executive functions in Parkinson's disease
7. Motor symptoms and phenotype in patients with Parkinson's disease dementia
8. Interaction between cognition and gait in patients with Parkinson's disease
9. Disorders of sleep and autonomic function in Parkinson's disease dementia
10. Structural and functional neuroimaging in patients with Parkinson's disease dementia
11. Biomarkers for cognitive impairment and dementia in Parkinson's disease
12. Electrophysiological and other auxiliary investigations in patients with Parkinson's disease dementia
13. Genetic basis of dementia in Parkinson's disease
14. Neurochemical pathology of Parkinson's disease dementia and dementia with Lewy bodies
15. Pathological correlates of dementia in Parkinson's disease
16. Epidemiology, diagnosis and correlates of Mild Cognitive Impairment in Parkinson's disease
17. The pathophysiological and prognostic heterogeneity of Mild Cognitive Impairment in Parkinson's disease
18. Spectrum of Lewy body dementias: relationship of Parkinson's disease dementia to dementia with Lewy bodies
19. Spectrum of disorders with dementia and Parkinsonism
20. Diagnosis of dementia in Parkinson's disease
21. Management of Parkinson's disease, dementia and dementia with Lewy bodies
22. Parkinson's disease: what will the future bring?