Oxford Textbook of Epilepsy and Epileptic Seizures

ISBN : 9780199659043

Simon D. Shorvon; Renzo Guerrini; Mark Cook; Samden Lhatoo
400 ページ
226 x 281 mm
Oxford Textbooks in Clinical Neurology

Epilepsy is the most common serious neurological condition, affecting children and adults, and can occur in a variety of medical settings. It has many causes and many forms, and a variable prognosis. Mortality and morbidity are high, social and legal consequences can stretch well beyond the purely medical, and its management is often poor. Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy and epileptic seizures. Written by internationally-renowned specialists, each chapter comprehensively covers the current knowledge and evidence base related to each aspect of the disorder, with an emphasis on the personal experience of the authors. The print edition of the Oxford Textbook of Epilepsy and Epileptic Seizures is complemented by an online version, which allows access to the full content of the textbook, contains links from the references to primary research journal articles, enables full text searches, and provides access to figures and tables that can be downloaded to PowerPoint(R). This textbook will prove a useful clinical reference for neurologists and senior trainees in neurology, an educational manual for trainees, and will offer practical assistance to all physicians advising people with epilepsy.


1. Neurophysiology of epilepsy
2. Neurogenetics of epilepsy
3. Neurochemistry of epilepsy
4. Developmental neurobiology, neuroanatomy, and neuropathology of epilepsy
5. Definitions and epidemiology of epilepsy
6. The causes of epilepsy
7. Classification, clinical symptoms, and syndromes
8. Differential diagnosis of epilepsy
9. EEG in the investigation of epilepsy
10. Neuroimaging in the Investigation of epilepsy
11. The biochemical, haematological, histological, immunological, and genetic investigation of epilepsy
12. Non-pharmacological therapy of epilepsy
13. Reproductive aspects of epilepsy
14. Neonatal seizures and infantile onset epilepsies
15. Epileptic encephalopathies
16. Principles of treatment of epilepsy in children and adolescents
17. Epilepsy in learning disability
18. Epilepsy in the elderly
19. Psychiatric co-morbidity in epilepsy
20. Epilepsy due to traumatic brain injury (TBI), cerebrovascular disease (CVD), central nervous system (CNS) infections and brain tumours
21. Epilepsy in renal, hepatic, and other conditions
22. Management of patients with first seizure and early epilepsy
23. The medical treatment of chronic active epilepsy
24. Epilepsy in remission
25. Drug interactions
26. The pharmacokinetics and clinical therapeutics of the antiepileptic drugs
27. Principles of epilepsy surgery
28. Resective surgery of temporal lobe epilepsy
29. Resective surgery of extra-temporal epilepsy
30. Vagal berve stimulation and deep brain stimulation in epilepsy
31. Other surgeries for epilepsy and new approaches
32. Management of seizures and of epilepsy in the emergency department
33. The management of status epilepticus on the intensive care unit
34. Epilepsy and employment
35. Sexual and emotional behaviour in epilepsy
36. Cognition and memory in adults
37. Legal aspects of epilepsy and epilepsy and driving


Simon Shorvon is a Professor of Neurology at the UCL Institute of Neurology, University College London, and a Consultant Neurologist at the National Hospital for Neurology and Neurosurgery, London, UK.; Renzo Guerrini is Professor of Child Neurology and Psychiatry, and Director of the Pediatric Neurology Unit and Laboratories at the Children's Hospital, A. Meyer-University of Florence, Italy. ; Mark Cook is Professor and Director of Neurology, St. Vincent's Hospital, Melbourne, Australia. ; Samden Lhatoo is a Professor of Neurology at the Department of Neurology, Case Western Reserve University Hospital, Cleveland, USA.