Textbook of Post-ICU Medicine: The Legacy of Critical Care

ISBN : 9780199653461

Robert D. Stevens; Nicholas Hart; Margaret S. Herridge
656 ページ
187 x 253 mm

Surviving critical illness is not always the happy ending we imagine for patients. Many ICU survivors suffer from a range of long-lasting physical and psychological issues such end stage renal disease, congestive heart failure, cognitive impairment, neuromuscular weakness, and depression or anxiety, which affect their overall quality of life and ability to lead productive lives. This lingering burden or 'legacy' of critical illness is now recognized as a major public health issue, with major efforts underway to understand how it can be prevented, mitigated, or treated. The Textbook of Post-ICU Medicine: The Legacy of Critical Care discusses the science of the recovery process and the innovative treatment regimens which are helping ICU survivors regain function as they heal following trauma or disease. Describing the major clinical syndromes affecting ICU survivors, the book delineates established or postulated biological mechanisms of the post-acute recovery process, and discusses strategies for treatment and rehabilitation to promote recovery in the ICU and in the long term. The chapters are written by an interdisciplinary panel of leading clinicians and researchers working in the field. The book serves as a unique reference for general practitioners, internists and nurses caring for long term ICU survivors as well as specialists in intensive care medicine, neurology, psychiatry, and rehabilitation medicine.


1. Life After the ICU
2. Critical Illness and Long-Term Outcomes Worldwide
3. Mortality After Critical Illness
4. The Role of Long-Term Ventilator Hospitals
5. The Overlap of Palliative Care and Critical Illness
6. Patterns of Recovery After Critical Illness
7. Quality of Life After Critical Illness
8. Costs and Resource Utilization in Prolonged Critical Illness
9. Caring for the ICU survivor: The Family Caregiver Burden
10. Survival and Recovery: A Patient's Perspective
11. One Family's Perspective on the Legacy of Critical Illness
12. Chronic Organ Dysfunction Following Critical Illness
13. Chronic Multiple Organ Dysfunction
14. Prolonged Respiratory Insufficiency and Ventilator Dependence in the ICU
15. The Long-Term Outcomes of Acute Kidney Injury
16. Severe Burn Injuries and Their Long-Term Implications
17. Consequences of Endotracheal Intubation and Tracheostomy
18. Cognitive and Behavioural Disorders Following Critical Illness
19. Cognitive Impairment Following Critical Illness
20. Depressive Mood States Following Critical Illness
21. Post-Traumatic Stress Disorder Following Critical Illness
22. Sleep Disorders and Recovery from Critical Illness
23. Neuromuscular and Musculoskeletal Disorders Following Critical Illness
24. Long-Term Implications of ICU-Acquired Muscle Weakness
25. Bone and Joint Disease Following Critical Illness
26. Biological Mechanisms of Injury and Repair
27. Genetic Determinants of Sepsis Outcomes
28. Physiological Reserve and Frailty in Critical Illness
29. Cognitive Reserve
30. Pathophysiology of Acute Kidney Injury, Repair, and Regeneration
31. Myocardial Remodelling after Myocardial Infarction
32. Sepsis-Associated Encephalopathy
33. Critical Illness Neuropathy, Myopathy, and Sodium Channelopathy
34. The Impact of Critical Illness and Skeletal Muscle Structure
35. Skeletal Muscle Mass Regulation in Critical Illness
36. Malnutrition in Critical Illness: Implications, Causes, and Therapeutic Approaches
37. Therapeutic and Rehabilitation Strategies in the ICU
38. Choice of Renal Replacement Therapy and Renal Recovery
39. Ventilator Liberation Strategies
40. Rethinking Sedation in the ICU
41. Sleep-Promoting Strategies
42. Effects of Insulin and Glycaemic Management on Neuromuscular Function
43. Physical and Occupational Therapy in the ICU
44. Neuromuscular Electrical Stimulation: A New Therapeutic and Rehabilitation Strategy in the ICU
45. Exercise and Early Rehabilitation in the Intensive Care Unit
46. Therapeutic and Rehabilitation Strategies in the Post-ICU
47. Assessment of Peripheral and Respiratory Muscle Strength in ICU
48. Clinical Pathways for the Continuum of Rehabilitation
49. Prolonged Weaning
50. Models of Rehabilitative Care after Critical Illness
51. Post-ICU Rehabilitation
52. Narratives of Illness and Healing after the ICU
53. ICU Follow-up Clinics


Robert D. Stevens, Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, USA; Nicholas Hart, Respiratory and Critical Care Medicine, National Institute of Health Research, Guy's & St Thomas' NHS Foundation Trust and King's College London, London, UK; Margaret S. Herridge, University Health Network, University of Toronto, Toronto, Canada