Cell Signalling

ISBN : 9780198859581

John Hancock
176 ページ
189 x 246 mm

Written primarily for students embarking on an undergraduate bioscience degree, this primer provides a clear introduction to the main aspects of cell signalling in biological systems, demystifying the subject for those new to the field. The primer provides an overview of cell signalling and highlights its importance in all organisms, before going on to describe the main components of cell signalling and examples of signal transduction pathways. The discussion then progresses on to key physiological conditions in which cell signalling has an instrumental role: cancer, apoptosis and diabetes. After getting to grips with the fundamentals of the subject, Cell Signalling opens a discussion on the future of the discipline, including how manipulation of cell signalling pathways is seen as the biggest target for the pharmaceutical industry, and how crop diseases, plant survival during stress, and post-harvest storage are all influenced by cell signalling pathways. Cell Signalling is supported by online resources and is available for students and institutions to purchase in a variety of formats. The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks The online resources include: For students: - Self-test questions For registered adopters of the book: * Figures from the book, available to download


1 Introduction to cell signalling
2 Signals and their perception
3 Modifications to proteins that control cell signalling
4 Intracellular signals
5 Cell signalling disorders
cancers and apoptosis
6 Stress responses and the changing cell environment
7 Future challenges and perspectives in cell signalling


John Hancock has worked in the area of cell signalling for over 30 years and on ResearchGate has over 170 research items listed. He has already authored a major textbook called Cell Signalling (now 4th ed.) published by OUP. Having studied for a BSc in Biochemistry he stayed at the University of Bristol, completing his PhD before remaining in the same department as a researcher for six years. In 1993 he took a post at the University of the West of England, Bristol, where he has remained ever since, being promoted to professor in January 2016. He has researched extensively on redox signalling in a range of organisms and has taught cell signalling to undergraduates and postgraduates for the last 25 years. He regularly attends and contributes to international conferences on nitric oxide signalling and the role of reactive oxygen species on biological systems, as well as writing numerous reviews and book chapters.