50 Studies Every Internist Should Know

ISBN : 9780199349937

Kristopher Swiger; Joshua R. Thomas; Steven Hochman; Michael E. Hochman
352 ページ
156 x 234 mm

50 Studies Every Internist Should Know presents key studies that have shaped the practice of internal medicine. Selected using a rigorous methodology, the studies cover topics including: preventative medicine, endocrinology, hematology and oncology, musculoskeletal diseases, nephrology, gastroenterology, infectious diseases, cardiology, pulmonology, geriatrics and palliative care, and mental health. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical practice.


Section 1. Preventive Medicine
1. Preventing Diabetes: The Diabetes Prevention Program
2. Dietary Approaches to Stop Hypertension (DASH)
3. Aspirin for the Primary Prevention of Cardiovascular Disease: The Physicians' Health Study and the Women's Health Study
4. Postmenopausal Hormone Therapy: The Women's Health Initiative
5. The Cochrane Review of Screening Mammography
6. The European Randomized Study of Screening for Prostate Cancer
7. Screening for Lung Cancer with Low-Dose Computed Tomography vs. Chest Radiography: The National Lung Screening Trial (NLST)
Section 2. Endocrinology
8. Treating Elevated Blood Sugar Levels in Patients with Type 2 Diabetes: the United Kingdom Prospective Diabetes Study (UKPDS)
9. Intensive versus conservative blood sugar control for patients with type 2 diabetes: the ACCORD trial
10. Intensive vs. Conventional Glycemic Control in Type 1 Diabetes Mellitus (DCCT)
11. Intensive vs. Conservative Blood Pressure Control in Patients with Type 2 Diabetes
Section 3. Hematology and Oncology
12. Choice of Anticoagulant for Prevention of Recurrent Venous Thromboembolism in Patients with Cancer
13. Vena Caval Filters in the Prevention of Pulmonary Embolism in Patients with Proximal Deep-Vein Thrombosis
14. Phase I Study of Imatinib (STI571) in Patients with Chronic Myelogenous Leukemia
Section 4. Musculoskeletal Diseases
15. Magnetic Resonance Imaging for Low Back Pain
16. Early therapy for rheumatoid arthritis: The TICORA Study
Section 5. Nephrology
17. Revascularization vs. Medical Therapy for Renal Artery Stenosis
18. Correcting Anemia in Chronic Kidney Disease: The CHOIR Study
19. Early versus Late Initiation of Dialysis: The IDEAL Trial
Section 6. Gastroenterology
20. Use of IV Albumin in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis
21. Early use of transjugular intrahepatic portosystemic shunt (TIPS) in patients with cirrhosis and variceal bleeding
Section 7. Infectious Diseases
22. Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department
23. Antibiotic Therapy in Exacerbations of Chronic Obstructive Pulmonary Disease
24. Early versus Delayed Antiretroviral Therapy for Patients with HIV: The NA-ACCORD Study
Section 8. Cardiology
25. Statins in Healthy Patients with an Elevated C-Reactive Protein: The JUPITER Trial
26. The Scandinavian Simvastatin Survival Study (4S)
27. Choosing Fist-Line Therapy for Hypertension: The ALLHAT Trial
28. Rate Control versus Rhythm Control for Atrial Fibrillation: The AFFIRM Trial
29. Initial Treatment of Stable Coronary Artery Disease: The COURAGE Trial
30. Early Invasive vs. Conservative Management for Unstable Angina or Non-ST-Elevation Myocardial Infarction: The RITA 3 Trial
31. MADIT II: Prophylactic Defibrillator Implantation in Patients with Low Ejection Fraction Following Myocardial Infarction
32. Captopril in Patients with Left Ventricular Dysfunction after Myocardial Infarction: The SAVE Trial
33. Spironolactone in Advanced Heart Failure: The RALES Trial
34. The African American Heart Failure Trial (A-HeFT)
35. Intraaortic Balloon Support for Myocardial Infarction with Cardiogenic Shock (IABP-SHOCK II)
Section 9. Pulmonary and Critical Care Medicine
36. Intensive versus Conventional Glucose Control in Critically Ill Patients
37. Red Cell Transfusion in Critically Ill Patients: The TRICC Trial
38. Noninvasive Ventilation for Acute Exacerbations of Chronic Obstructive Pulmonary Disease
39. Low Tidal Volume Ventilation in Acute Respiratory Distress Syndrome/Acute Lung Injury
40. Comparison of routine vs. on-demand chest radiographs in mechanically-ventilated adults in the intensive care unit
41. Early Goal-Directed Therapy in Sepsis
42. Dopamine vs. norepinephrine in the treatment of shock
43. Daily Interruption of Sedative Infusions in Critically Ill Patients Undergoing Mechanical Ventilation
44. A Comparison of Four Methods of Weaning Patients from Mechanical Ventilation
Section 10. Geriatrics and Palliative Care
45. Behavioral versus Pharmacological Treatment for Insomnia in the Elderly
46. Treatment of Hypertension in the Elderly
47. Use of feeding tubes in patients with dementia
48. Early Palliative Care in Non-Small-Cell Lung Cancer
Section 11. Mental Health
49. Initial Treatment of Depression
50. Symptom-Triggered vs. Fixed Dose Therapy for Alcohol Withdrawal


MH: Medical Director for Innovation, AltaMed Health Services and Robert Wood Johnson Foundation Clinical Scholar, Department of Internal Medicine, University of California, Los Angeles. CNP: Fellow, Division of Cardiology, University of Pennsylvania School of Medicine.