Myositis (ORL)

ISBN : 9780198754121

Hector Chinoy; Robert G. Cooper
192 ページ
138 x 216 mm
Oxford Rheumatology Library

The idiopathic inflammatory myopathies (IIM) are a rare group of autoimmune diseases, negatively affecting the lives of an estimated 250,000 people worldwide. Delays in diagnosis often occur owing to a lack of recognition of disease presentation, or misdiagnosis, both of which can lead to muscle atrophy. This new addition to the Oxford Rheumatology Library series focuses on providing a summary of what is currently understood about the epidemiology of myositis, controversies in diagnosis criteria, clinical features, and the current paradigms for treatment and intervention. Designed to bring together the multi-disciplinary involvement of healthcare professionals for IMM patients, this is the first easy-to-navigate guide for the practical management of myositis. This is an essential guide for both physicians and trainees in Rheumatology, Neurology, and Dermatology specialities.


Overview of Myositis; 1 Vidya Sadanand Limaye: Overview and epidemiology; 2 Anna Tjarnlund and Ingrid E. Lundberg: Diagnostic and classification criteria; 3 Joanna E Parkes, Simon Rothwell, and Janine A Lamb: Aetiology and pathogenesis; 4 Jens Schmidt: Extra-muscular complications occurring in myositis; Differential Diagnosis; 5 James Lilleker and Mark Roberts: Metabolic Myopathies; 6 Stefen Brady and David Hilton-Jones: Muscular dystrophies and other genetic myopathies; 7 Andrew Mammen and Jessica Nance: Investigation of hyperCKaemia; Important Disease Subtypes and Associations; 8 Albert Selva-O'Callaghan and Ernesto Trallero-Araguas: Association with malignancy; 9 Arash H Lahouti and Lisa Christopher-Stine: Toxic myopathies; 10 Lucy Wedderburn, Kiran Nistala, and Christina Boros: Juvenile Myositis; 11 Pedro M Machado: Inclusion body myositis (IBM); Investigations; 12 Sarah Tansley and Neil McHugh: Laboratory features - enzymes & biomarkers; 13 Marianne de Visser: Histopathological features of the idiopathic inflammatory myopathies (IIM); 14 Nicolo Pipitone and Ranjit Ramdass: Imaging of skeletal muscle; 15 Ranjit Ramdass: Neurophysiology in the assessment of inflammatory myopathies; Outcome and Treatment; 16 Lisa G Rider and Frederick W Miller: Outcome assessment in the idiopathic inflammatory myopathies; 17 Ji?i Vencovsky and He?man Mann: Treatment of the idiopathic inflammatory myopathies


Dr Hector Chinoy Dr Chinoy is a Senior Clinical Lecturer in Rheumatology at the University of Manchester, UK, and an Honorary Consultant Rheumatologist at Salford Royal Hospital. He is on the editorial board for the European Medical Journal and Reumatologia, and is the principal investigator of the UK Medical Research Council funded prospective myositis cohort collection, MYOPROSP. His research interests include the genetic, epidemiological, and clinical aspects of adult myositis. ; Professor Robert G Cooper Professor Cooper is the Chair of Medicine (Muscle and Rheumatology) in the MRC/Arthritis Research UK Institute for Ageing and Chronic Disease in the University of Liverpool, and an honorary Chair in the Centre for Integrated Genomic Medical Research in the University of Manchester. He has a long-standing research interest in the immunogenetic basis for myositis, and has worked on the development of myositis-specific antibodies.