ISBN : 9780190280253
Neuroprotection is becoming an increasingly recognized and important part of critical care and perioperative medicine. As human beings survive increasingly severe life-threatening injuries and complex surgical interventions, it has become clear that neurologic injury and dysfunction is a primary driver of long-term outcome and disability. Neuroprotection is currently under-recognized as the primary objective in promoting recovery from life-threatening injuries, illnesses, and procedures.
To address this knowledge gap, Neuroprotection in Critical Care and Perioperative Medicine provides a concise review of the current state of the art of clinical care and research. Within the context of critical care, the specific topics covered will include the primary forms of brain injury on which neuroprotection research and intervention has traditionally focused, such as traumatic brain injury, cardiac arrest, acute ischemic stroke, and intracranial hemorrhage, as well as CNS injuries related to sepsis and acute respiratory distress syndrome, mechanical circulatory support, and premature birth. Within the context of perioperative care, the specific topics covered will include anesthetic and perioperative strategies to reduce brain injury from cardiac surgery, aortic surgery and endovascular repair, carotid endarterectomy, vascular and endovascular neurosurgery, and other major surgical procedures.
PROTECTION STRATEGIES; 1. Physiologic Modulators of Neural Injury After Brain and Spinal Cord Injury; W. Dalton Dietrich; 2. Pharmacologic Neuroprotection; Nino Stocchetti and Marco Carbonara; CLINIMETRICS OF NEUROPROTECTION; 3. Imaging Assessment of Brain Injury; Matthew A. Warner, Carlos Marquez de la Plata, David S. Liebeskind, and Ramon Diaz-Arrastia; 4. Tissue Biomarkers and Neuroprotection; Axel Petzold; 5. Neurophysiological Monitoring and Neuroprotection; Aws Alawi, Michael Reznik, Jan Claassen; 6. Neurological and Functional Outcomes Assessment; Suzan Uysal and Stephan A. Mayer; 7. Assessment of Postoperative Cognitive Decline; Suzan Uysal and David L. Reich; NEUROPROTECTION IN CRITICAL CARE; 8. Neuroprotection for Traumatic Brain Injury; Jonathan J. Ratcliff and David W. Wright; 9. Neuroprotection for Cardiac Arrest; Joseph Pitcher and David B. Seder; 10. Neuroprotection for Acute Ischemic Stroke; Diana Mayor and Michael Tymianski; 11. Neuroprotection for Intracranial Hemorrhage; Julius Griauzde, Neeraj Chaudhary, Joseph J Gemmete, Aditya S Pandey, Guohua Xi; 12. Neuroprotection for Mechanical Circulatory Support; Lauren E Dunn, Joshua Z Willey, Ronald M Lazar; 13. Neuroprotection in Sepsis and Acute Respiratory Distress Syndrome; Neha S. Dangayach, Charles L Francoeur, Stephan A. Mayer, Tarek Sharshar; 14. Neuroprotection for Premature Birth and Neonatal Brain Injury; Eugene Chang; 15. Neuroprotection for Spinal Cord Injury; Christopher S. Ahuja and Michael Fehlings; PERI-OPERATIVE NEUROPROTECTION; 16. Neuroprotection for Valvular and Coronary Bypass Surgery; Karsten Bartels G. Burkhard Mackensen; 17. Neuroprotection for Aortic Surgery and Stenting; Jared W. Feinman and John G. Augoustides; 18. Neuroprotection for Carotid Endarterectomy and Stenting; Zirka H. Anastasian and Eric J. Heyer; 19. Neuroprotection for Vascular and Endovascular Neurosurgery; Travis R Ladner, Nishant G Kumar, Lucy He, J Mocco; 20. Neuroprotection for Spine Surgery; Jess W. Brallier and Jonathan S. Gal; 21. Neuroprotection for General, Orthopedic, Peripheral Vascular and ENT Surgery; Magdy Selim