Antimicrobial Stewardship

ISBN : 9780198758792

Matthew Laundy; Mark Gilchrist; Laura Whitney
182 ページ
171 x 246 mm

Antimicrobial resistance (AMR) challenges the treatment of clinical infections. Despite the decline in infectious diseases mortality rates, infections are more difficult to eliminate or contain in the host, resulting in poorer outcomes to treatment, longer hospital inpatient stays, and increased mortality. Written by international experts in the field and supported by the review of the available evidence, including example case studies, Antimicrobial Stewardship provides a practical how-to guide on this growing area. Divided into three sections, the first sets the scene, looking at the key problems of antimicrobial resistance. Section two examines and identifies the key components of an antimicrobial stewardship program. Finally, the book explores specialist areas of antimicrobial stewardship ranging from antimicrobial pharmacokinetics and dynamics, to near patient testing, and infection biomarkers. Antimicrobial Stewardship will be a valuable and practical resource for infection trainees, as well as specialists from the medical, pharmacy, and nursing professions.


Section 1: Setting the scene and starting up:
1 Susan Hopkins: The international and national challenges faced in ensuring the prudent use of antimicrobials
2 Fiona Robb and Andrew Seaton: What are the principles and goals of antimicrobial stewardship
3 Esmita Charani and Gabriel Birgand: Managing behaviours: Social, cultural and psychological aspects of antibiotic prescribing and use
4 Patrick Doyle: Implementing an Antimicrobial Stewardship Programme
Section 2: Components of an Antimicrobial Stewardship Program
5 Antonia Scobie, Mark Gilchrist, Laura Whitney and Matthew Laundy: Managing antimicrobials on the shop floor
6 Hayley Wickens: Measuring antibiotic consumption and outcomes
7 Jacqueline Sneddon and Billy Malcolm: Measuring and feeding back stewardship
8 Matthew Laundy: Information technology in antimicrobial stewardship
Section 3: Special Areas in Antimicrobial Stewardship
9 Jason Roberts and Menino Osbert Cotta: Pharmacokinetic and Pharmacodynamic Principles of Antimicrobials
10 Peter Riley: The Role of the Microbiology Laboratory in Antimicrobial Stewardship
11 Haifa Lyster: Antimicrobial Stewardship in the Immuno-Compromised Patient
12 Jonathan Ball: Antimicrobial Stewardship in the Intensive Care Setting
13 Tamsin Oswald, Simon Jameson, Mike Reed: Surgical Prophylaxis
14 Sanjay Patel and Julia Bielicki: Antimicrobial Stewardship in Paediatrics
15 Naomi Flemming: Stewardship in the primary care and long term care setting
16 Laura Whitney and Tihana Bicanic: Antifungal Stewardship
17 Matthew Dryden: Near Patient Testing and infection biomarkers
18 Marc Mendelsohn: Antimicrobial Stewardship in a Resource Poor Setting


Matthew Laundy is a consultant microbiologist at St George's University Hospitals NHS Foundation Trust. He has a special interest in antimicrobial stewardship, OPAT, paediatric infections and medical informatics. He is a Fellow of the Royal College of Pathologists and a member of the Royal College of Paediatrics and Child Health.; Mark Gilchrist is a Consultant Pharmacist in Infectious Diseases at Imperial College Healthcare NHS Trust, and an Honorary Lecturer at Imperial College, London. Mark has a specialist interest in Outpatient Parenteral Antimicrobial Therapy (OPAT) and global antimicrobial stewardship initiatives. Mark is a past chair of UK Clinical Pharmacy Infection Network and is a spokesman for the Royal Pharmaceutical Society on Antimicrobials. In 2013 Mark was awarded Fellow of the Royal Pharmaceutical Society Faculty.; Laura Whitney is a Consultant Antimicrobial Pharmacist at St George's University Hospitals NHS Trust and an Honorary Senior Lecturer at Kingston University. Her specialist interests include; antimicrobial stewardship, management of invasive fungal infections, and the treatment and prevention of Clostridium difficile infection. Laura is a member of the Royal Pharmaceutical Society of Great Britain and is a current committee member of the UK Pharmacy Infection Network.