Oxford Textbook of Advanced Heart Failure and Cardiac Transplantation

ISBN : 9780198734871

Michael Domanski; Mandeep R. Mehra; Marc Pfeffer
464 ページ
219 x 276 mm

Heart failure is epidemic throughout the world. A growing incidence and prevalence has resulted in a large population of individuals transitioning to advanced stages of the syndrome and requiring uniquely specialised therapies and cardiac transplantation. Oxford Textbook of Advanced Heart Failure and Cardiac Transplantation is a focused and comprehensive work covering this new and rapidly growing cardiovascular subspecialty. Authored by eminent international experts, it is the authoritative text on advanced heart failure and a central resource for clinicians caring for patients with this conditition. By covering a range of characteristics, therapeutic challenges and practical aspects of managing patients this book provides an in-depth source for cardiologists and other related clinicians. A strong focus on the difficult decision making needed to handle advanced heart failure cases, along with specific knowledge of epidemiology, biology and pathophysiology, creates a key tool for optimally managing these complex patients.


1 Marc A. Pfeffer, Michael Domanski and Mandeep R. Mehra: Advanced heart failure in perspective
2 Kenneth B. Marguiles and J.Eduardo Rame: Cell biology of heart failure
3 Julia Shin, Mandeep R. Mehra and Ileana Pena: Physiology and hemodynamic assessment of the failing heart: Current knowledge and unmet needs for advanced heart failure
4 James F. George: Transplantation immunology
5 Max J. Liebo and W.H. Wilson Tang: Implantable devices for cardiovascular monitoring
6 Michael J. Domanski, Mark Halushka and Sean Pinney: Endomyocardial biopsy in the failing heart
7 Mayank Kansal, Manish Bansal, Jagat Narula and Partho P Sengupta: Imaging in advanced heart failure
8 Akshay S. Desai and Marc A. Pfeffer: Pharmologic management of advanced heart failure
9 Steven Stevens, Kalyanam Shivkumar and Noel G. Boyle: Arrhythmias in heart failure: The AV node and above
10 John D. Ferguson and John P. DiMarco: Ventricular Arrhythmias in Heart Failure
11 James P. Daubert, Brett Atwater and Kevin Jackson: Cardiac Resynchronization
12 Blase A. Carabello: Advanced heart failure in valvular heart disease
13 Marzia Leacche, Garrick C. Stewart and John G. Byrne: High risk heart failure surgery: strategies for coronary artery bypass grafting and valve surgery in patients with reduced ejection fraction
14 Michael J. Domanski and Mandeep R. Mehra: Mechanical circulatory support: patient selection, optimization and inpatient management of the LVAD patient
15 Mandeep R. Mehra and Michael J. Domanski: Mechanical circulatory support: outpatient management
16 Joann Lindenfeld: Cardiac transplantation overview
17 Jon A. Kobashigawa: Immunosuppression strategies
18 Natasha Lipson and Sean P. Pinney: Rejection surveillance, type and treatment
19 Howard J. Eisen and Thomas J. Vischer: Complications after cardiac transplantation
20 Thomas G. DiSalvo and Simon Maltais: Right heart failure: Anatomy physiology and patho-biology
21 Thomas G. DiSalvo and Simon Maltais: Right ventricular failure: Clinical features and management
22 Myung Park: Pulmonary arterial hypertension
23 Jessi Khangura and Sarah J. Goodlin: End of life care in advanced heart failure
24 Michael Domanski, Mark Pfeffer and Mandeep R. Mehra: Future directions in advanced heart failure


Michael Domanski is a Professor of Medicine at University Health Network, Peter Munk Cardiovascular Centre and the University of Toronto. He is also the Director of Heart Failure Research and the Patient Inpatient Heart Failure Program and Chairman of the Cardiovascular Clinical Trials Oversight Committee. Professor Domanski has previously held director positions at Trinity Medical Centre, North Dakota and Washington Adventist Hospital.; Mandeep Mehra is Professor of Medicine and Head of Cardiology at University of Maryland School of Medicine. He is also the Editor-in-Chief of The Journal of Heart and Lung Transplantation. Professor Mehra has previously been affiliated with Louisiana State University and was the Chief of Ochsner Clinic Foundation's Cardiomyopathy and Heart Transplantation Centre.; Marc Alan Pfeffer is a Senior Physician at Brigham and Women's Children Hospial, Boston, Massachusetts and Director of their Cardiovascular Grand Rounds program. He is a recipient of the American Heart Association Clinical Research Prize and is a Senior Associate Editor at Circulation. Professor Pfeffer previously held a position as a Professor of Medicine at Harvard Medical School.