ISBN : 9780199698073
Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Neuromuscular Disorders covers the scientific basis, clinical diagnosis, and treatment of neuromuscular disorders with a particular focus on the most clinically relevant disorders. The book is organized into seven sections, starting with the general approach to the patient with neuromuscular disorders and then focusing on specific neuromuscular conditions affecting the peripheral nervous system from its origins at the spinal cord anterior horn on its outward course to their effector muscles and the inbound sensory pathways. Chapters on specific neuromuscular conditions are illustrated with typical case histories and their presenting features, allowing readers to put rarer conditions into their clinical context more easily. The concurrent online version allows access to the full content of the textbook, contains links from the references to primary research journal articles, allows full text searches, and provides access to figures and tables that can be downloaded to PowerPoint(R). This textbook will serve as a useful reference for neurologists and specialist trainees in neurology, neuroscientists, neurophysiologists, and other healthcare professionals.
SECTION 1: APPROACH TO THE PATIENT
1. Eliciting the history
2. Genetic considerations
3. Examination
SECTION 2: ANTERIOR HORN
4. Amyotrophic Lateral Sclerosis
5. Spinal muscular atrophy and hereditary motor neuropathy
6. Kennedy's disease
7. Poliomyelitis
SECTION 3: PERIPHERAL NERVE: INHERITED
8. Charcot Marie Tooth disease
9. Hereditary sensory and autonomic neuropathies
10. Familial amyloid polyneuropathy
11. Inherited metabolic neuropathies
SECTION 4: PERIPHERAL NERVE: ACQUIRED
12. Mononeuropathies
13. Multiple mononeuropathies
14. Plexopathy
15. Polyneuropathies: Axonal
16. Polyneuropathies: Demyelinating
17. Diabetic neuropathy
18. Peripheral nerve hyperexcitability disorders
SECTION 5: NEUROMUSCULAR JUNCTION: INHERITED AND ACQUIRED
19. Inherited myasthenic syndromes
20. Myasthenia gravis
21. The Lambert-Eaton myasthenic syndrome
SECTION 6: MUSCLE
22. The dystrophinopathies
23. Limb-girdle muscular dystrophies
24. The congenital muscular dystrophies
25. The myotonic dystrophies
26. FSH dystrophy
27. Distal myopathies and myofibrillar myopathies
28. Congenital/ultrastructural myopathies
29. Metabolic myopathies
30. Mitochondrial cytopathies
31. Skeletal muscle channelopathies
32. Idiopathic inflammatory myopathies
33. Drug-induced neuromuscular disorders
34. Endocrine myopathies
SECTION 7: ACUTE NEUROMUSCULAR CONSULTS
35. The neuromuscular emergency consult
36. Critical care of neuromuscular disorders