Oxford Textbook of Stroke and Cerebrovascular Disease

ISBN : 9780199641208

Bo Norrving
304 ページ
224 x 282 mm
Oxford Textbooks in Clinical Neurology

Stroke is a major health concern worldwide, and the epidemiological data is staggering. One in six people will have a stroke during the course of their life; it is the second most common cause of death; and stroke also ranks second among causes contributing to the global burden of disability. However, the burden of stroke can be alleviated: it is potentially preventable, treatable, and possible to manage long term. Despite continuing advances in our knowledge about this disease, there is currently still a large evidence-to-clinical practice gap in all regions. The Oxford Textbook of Stroke and Cerebrovascular Disease is a comprehensive textbook on clinical stroke, covering all major aspects of cerebrovascular disease including epidemiology, risk factors, primary prevention, pathophysiology, diagnostics, clinical features, acute therapies, secondary prevention, prognosis, and rehabilitation. It makes use of current pedagogic principles, and includes not only aspects on management in the acute hospital phase of stroke, but also public health issues, prevention, long-term management, and silent vascular disease (which is becoming increasingly epidemic in the general population). Topical aspects also include advice to improve clinical skills in examination, diagnosing, and treating stroke. The text also covers the fields of silent cerebrovascular disease (silent brain infarcts, microbleeds, white matter ischemic abnormalities) that more recently have been recognized to be highly prevalent in the general population, and that carry important risks on vascular events and cognitive decline/dementia. Chapters are written by a most distinguished group of international experts in the field of stroke from around the world, and have been carefully edited to ensure consistency in style and clarity of contents. The concurrent online version allows access to the full content of the textbook, contains links from the references to primary research journal articles, allows full text searches, and provides access to figures and tables that can be downloaded to PowerPoint(R). Practical, easy to use, yet detailed with respect to pathophysiology, diagnostics, and management, this text provides a source of reference for the detection and management of all stroke and less common cerebrovascular diseases for practising and trainee neurologists, geriatricians, and all stroke physicians and clinicians.


1. Epidemiology of stroke
2. Risk factors
3. Arteries and veins of the brain: Anatomical organization
4. Pathophysiology of TIA and ischemic stroke
5. Pathophysiology of non-traumatic intracerebral haemorrhage (ICH)
6. Spontaneous Intracranial Subarachnoid Haemorrhage: Epidemiology, causes, diagnosis and complications
7. Clinical features of transient ischemic attacks
8. Clinical features of acute stroke
9. Diagnosing TIA and stroke
10. Management of stroke: general principles
11. Acute phase therapies in ischemic stroke
12. Acute management and treatment of intracerebral
13. Acute treatment in SAH
14. Less common causes of stroke: diagnosis
15. Secondary prevention of stroke
16. Prognosis after stroke
17. Silent cerebral infarcts and microbleeds
18. Complications after stroke
19. Vascular cognitive impairment and dementia
20. Brain repair after stroke
21. Rehabilitation after stroke
22. The long term management of stroke
23. Primary prevention of stroke
24. Organization of stroke services


Bo Norrving is Professor of Neurology at Lund University, Sweden. He was corresponding author of the Swedish Aspirin Low-Dose Trial (SALT) (Lancet, 1991), the first trial demonstrating the benefit of low dose aspirin therapy for the prevention of stroke. He pioneered the assessment of cerebral hemodynamics by blood flow techniques, clinical syndromes of cerebellar stroke and lacunar infarcts, the importance of silent small vessel disease in the brain, and recognition of dissection as a major cause of stroke in the young. He is Chair of the steering committee of SIFAP, and a founder of Riks-Stroke, the world's first national stroke registry. He is Senior Consulting Editor of Stroke, Associate Editor of Neuroepidemiology, and member of several editorial boards. Bo Norrving was the President of the World Stroke Organisation between 2008 and 2012 and still represents the society at the WHO and UN. He chairs the Cerebrovascular Committee for the revision of the ICD 11 at the WHO.