OXFORD UNIVERSITY PRESS

Let's Go Special Pack
 

Foundations of the Neuron Doctrine (25th Anniversary edition)

ISBN : 9780190259389

参考価格(税込): 
¥11,396
著者: 
Gordon M. Shepherd. DPhil.
ページ
384 ページ
フォーマット
Hardcover
サイズ
156 x 235 mm
刊行日
2015年12月
メール送信
印刷

The neuron doctrine, first formulated in 1891, states that the brain is constructed of individual neurons, organized into functioning circuits that mediate behavior. Above all else, this is the main concept that underlies all of modern neuroscience. This 25th Aniversary Edition of The Foundations of the Neuron Doctrine explains how this theory was the product of an explosion of histological studies and vigorous debates near the end of the nineteenth century by an extraordinary group of scientists, most importantly the leading figure of the time, Santiago Ramon y Cajal of Spain, and includes the foremost nervous system investigators of many countries, such as Albrecht Kolliker, Sigmund Freud, Wilhelm His, August Forel, Fritdjof Nansen and Gustav Retzius. The neuron doctrine explains how these eminent scientists used a selective nerve cell stain invented by Camillo Golgi of Italy and followed him in describing the fabulous branching patterns of nerve cells, providing strong evidence that the cells interact as individual units to form circuits. This work also describes how this view was opposed by Golgi, who maintained that the nerve cells form syncytial networks. Studies in the 1950s appeared resoundingly to confirm the nerve cell as an individual unit, as embodied in the neuron doctrine, which became the basis for the rise of concepts of normal and disordered neural function in the remaining 20th century. This 25th Anniversary Edition concludes by discussing how recent studies are showing a much greater degree of complexity in neuronal organization, so that the debate of neuron versus network is again coming to the fore of neuroscience research. Unique to this anniversary edition is the inclusion of commentaries by distinguished leaders in the neurosciences on the continuing relevance of the neuron doctrine for modern studies of the brain at all levels, from genes and molecules to microcircuits, neural networks, and behavior.

目次: 

Preface
Commentaries on The Neuron Doctrine
Cajal, Golgi and Ariadne's Needle - Marina Bentivoglio
Reflections on the Neuron Doctrine - Javier DeFelipe
The Neuron Doctrine Revisited: A Personal Account - Sten Grillner
Camillo Golgi, Foundations of the Neuron Doctrine, and the
History of Neurosciences - Paolo Mazzarello
Some Reflections on the Neuron Doctrine - Larry Swanson
1. Introduction
2. From the Beginnings to the Cell Theory
3. Do Nerve Cells Belong in the Cell Theory?
4. Nerve Cells or Nerve Nets?
5. Kolliker Gives In
6. Support Builds for Network
7. The Nerve Cell Studies of Freud
8. The Revolutionary Method of Golgi
9. A Neuron Theory Begins to Take Form: His, Forel, Nansen
10. Ramon y Cajal: The Shock of Recognition
11. The Early Discoveries of Cajal
12. The Laws of Cajal
13. Joining the Mainstream
14. The Neuron Doctrine
15. The Law of Dynamic Polarization
16. Controversy
17. The Synapse and the Growth Cone
18. Forging a Consensus
19. Confrontation in Stockholm
20. Modern Revisions of the Neuron Doctrine
Comment on Sources
References
Index

著者について: 

Gordon M. Shepherd is Professor of Neurobiology at Yale University School of Medicine. He carries out research on the olfactory pathway as a simple system for the microcircuit organization of the brain. He is a former Editor-in-Chief of the Journal of Neurophysiology and Journal of Neuroscience. His books include Handbook of Brain Microcircuits (edited with Sten Grillner) and Creating Modern Neuroscience.

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