Tourette Syndrome

ISBN : 9780199796267

Davide Martino; James F. Leckman
714 ページ
187 x 256 mm

Tourette syndrome (TS) is finally recognized as a common neurodevelopmental disorder, and has gained increasingly high social awareness and scientific interest worldwide. Knowledge of its clinical presentation, mechanisms of disease, and available treatment approaches has increased remarkably over the last decade. Likewise, the way clinicians, teachers, social care workers and families face the problems manifested by patients with TS is rapidly evolving. Tourette Syndrome, edited by Davide Martino and James F. Leckman, offers a unique opportunity to capture this interesting momentum through a comprehensive and up-to-date overview. Tourette Syndrome covers all of the main aspects related to TS, analyzing the complexity of its clinical presentation, the novel viewpoints of causes and mechanisms, the best way to assess TS patients, and the multifaceted and multidisciplinary treatment options. The multidisciplinary and up-to-date content is the main asset of this volume, which represents a useful source of consultation for a wide audience of professionals, all of whom will have access to what is known so far on TS within their particular area of expertise, at the same time being able to expand and update their knowledge in other areas. Medical and PhD students, as well as post-doctoral scientists, will be able to use the volume as a valuable learning source. Also, questions for future research are clearly presented in the volume, providing a summary of the viewpoint of the contributing authors upon where research on TS should be heading. Finally, clinicians and other health professionals will have access at a glance to the main patients' associations and organizations dedicated to TS worldwide, which can facilitate the direct contact with patients.


Chapter 1 Phenomenology of tics and sensory urges: the self under siege
James F Leckman, Michael H Bloch, Denis G Sukhodolsky, Lawrence Scahill, Robert A King (Child Study Center, Yale University, New Haven, CT, USA)
Chapter 2 The phenomenology of attention deficit hyperactivity disorder in Tourette syndrome
Aribert Rothenberger (University of Gottingen, Germany) and Veit Roessner (University Medical Center, Dresden, Germany)
Chapter 3 The phenomenology of obsessive-compulsive symptoms in Tourette syndrome
Ygor A Ferrao (Universidade Federal de Ciencias de Saude de Porto Alegre, Brazil), Pedro G de Alvarenga, Ana G Hounie, Maria Alice de Mathis, Maria C de Rosario and Euripedes Miguel (University of Sao Paulo Medical School, Brazil)
Chapter 4 Other psychiatric co-morbidities in Tourette syndrome
Danielle Cath (Utrecht University, The Netherlands) and Andrea Ludolph (University of Ulm, Germany)
Chapter 5 Clinical course and adulthood-outcome in Tourette syndrome
Michael Bloch (Yale Child Study Center, New Haven, CT, USA)
Chapter 6 Prevalence and methods for population screening
Lawrence Scahill (Yale Child Study Center, New Haven, CT, USA) and Soren Dalsgaard (Denmark)
Chapter 7 Genetic susceptibility in Tourette syndrome
Thomas Fernandez and Matthew W State (Child Study Center, Yale University, New Haven, CT, USA)
Chapter 8 Perinatal adversities and Tourette syndrome
Pieter J Hoekstra (University of Groningen, The Netherlands)
Chapter 9 Infections and tic disorders
Tanya K Murphy (University of Florida College of Medicine, Gainesville, FA, USA)
Chapter 10 Cellular and molecular pathology in Tourette syndrome
Flora M Vaccarino, Yuko Kataoka and Jessica Lennington (Child Study Center, Yale University, New Haven, CT, USA)
Chapter 11 Electrophysiology in Tourette syndrome
Michael Orth (University of Ulm, Germany)
Chapter 12 Neurobiology and functional anatomy of tic disorders
Deanna J Greene, Kevin J Black, Bradley L Schlaggar (University of Washington, St. Louis, MO, USA)
Chapter 13 The Neurochemistry of Tourette syndrome
Harvey S Singer (Johns Hopkins University School of Medicine, Baltimore, MD, USA)
Chapter 14 Immunity and stress response in Tourette syndrome
Davide Martino (Queen Mary University of London, London, UK)
Chapter 15 Animal models of tics
Kevin W McCairn, Yukio Imamura and Masaki Isoda (Okinawa Institute of Science and Technology, Okinawa, Japan)
Chapter 16 Whither the relationship between etiology and phenotype in Tourette syndrome?
Mary M Robertson (St. George's Hospital and Medical School, London, UK) and Valsamma Eapen (University of New South Wales, Sydney, Australia)
Chapter 17 The differential diagnosis of tic disorders
Roger Kurlan (Atlantic Neuroscience Institute, Summit, NJ, USA)
Chapter 18 Comprehensive assessment strategies
Robert A King and Angeli Landeros-Weisenberger (Child Study Center, Yale University, New Haven, CT, USA)
Chapter 19 Clinical rating instruments in Tourette syndrome
Andrea E Cavanna and John CP Piedad (University of Birmingham, Birmingham, UK)
Chapter 20 Neuropsychological assessment in Tourette syndrome
Tara Murphy (Great Ormond Street Hospital for Children, London, UK) and Clare Eddy (University of Birmingham, Birmingham, UK)
Chapter 21 Social and adaptive functioning in Tourette syndrome
Denis G Sukhodolsky, Virginia W Eicher and James F Leckman (Child Study Center, Yale University, New Haven, CT, USA)
Chapter 22 Psychoeducational interventions: what every parent and family member needs to know
Eli R Lebowitz and Lawrence Scahill (Child Study Center, Yale University, New Haven, CT, USA)
Chapter 23 Cognitive-behavioural treatment for tics
Matthew R Capriotti and Douglas W Woods (University of Wisconsin, Milwaukee, WI, USA)
Chapter 24 Pharmacological treatment of tics
Veit Roessner (University Medical Center, Dresden, Germany) and Aribert Rothenberger (University of Gottingen, Germany)
Chapter 25 Treatment of psychiatric co-morbidities in Tourette syndrome
Francesco Cardona (University of Rome ", Rome, Italy) and Renata Rizzo (University of Catania, Catania, Italy)
Chapter 26 Surgical treatment of Tourette syndrome
Mauro Porta, Marco Sassi and Domenico Servello (IRCCS Galeazzi, Milan, Italy)
Chapter 27 Alternative treatments in Tourette syndrome
Beata Zolovska and Barbara Coffey (NYU Child Study Center, New York City, NY, USA)
Chapter 28 Information and social support for patients and families
Kirsten Muller-Vahl (Hannover Medical School, Hannover, Germany)
Chapter 29 Information and support for educators
Sheryl K Pruitt (Parkaire Consultants, Marietta, GA, USA) and Leslie E Packer (Tourette Syndrome Association, Long Island Chapter)
Chapter 30 Tourette syndrome support organisations around the world
Louise Roper (University of Birmingham, Birmingham, UK), Peter Hollenbeck (Purdue University, West Lafayette, IN, USA) and Hugh Rickards (University of Birmingham, Birmingham, UK)


Dr. Davide Martino is a Clinical Lecturer at Queen Mary University of London and Consultant Neurologist at the South London NHS Trust. His clinical and research activity is devoted to Tourette syndrome and other movement disorders. He is a co-founder of the European Society for the Study of Tourette syndrome (ESSTS) and has published more than 70 articles, many of which focused on phenomenology, immunological aspects and imaging of Tourette syndrome. James F. Leckman is Neison Harris Professor in the Child Study Center and Professor of Pediatrics and of Psychiatry at Yale University School of Medicine, New Haven, CT.