Rating Scales in Parkinson's Disease: Clinical Practice and Research

ISBN : 9780199783106

Cristina Sampaio; Christopher G. Goetz; Anette Schrag
342 ページ
184 x 255 mm

For many years, the need to develop valid tools to evaluate signs and symptoms of Parkinson Disease (PD) has been present. However the understanding of all intricacies of rating scales development was not widely available and the first attempts were relatively crude. In 2002, the Movement Disorders Society created a task force to systemize the measurement of Parkinson's Disease. Since then, the Task Force has produced and published several critiques to the available rating scales addressing both motor and non-motor domains of Parkinson Disease. Additionally the task force initiated a project to develop a new version of the UPDRS, the MDS-UPDRS. But none of this was made available in one convenient source. Until now. Rating Scales in Parkinson's Disease is written for researchers from the medical and social sciences, and for health professionals wishing to evaluate the progress of their patients suffering from Parkinson Disease. The book is both exhaustive in the description of the scales and informative on the advantages and limitations of each scale. As such, the text clearly guides readers on how to choose and use the instruments available. Extensive cross-referenced tables and charts closely integrate the parts of the book to facilitate readers in moving from one symptom domain to another.


Introduction, Cristina Sampaio, Christopher G. Goetz, and Anette Schrag
Part I: Measurement tools and how to interpret the validation data.
1. Clinical Rating Scale Development, Glenn Stebbins
2. Statistics for the Scale Developer, Barbara C.Tilley
3. How to Evaluate Validation Data, Paolo Martinez-Martin and Maria Joao Forjaz
4. The Minimal Clinically Relevant Change in Rating Scales, Cristina Sampaio, Olivier Rascol, and Anette Schrag
Part 2: Evaluation of Parkinson disease impairments and disabilities: history, methods and scales.
5. A Historical perspective on Rating Scales in PD: The Problems of Evaluating Impairments and Disabilities, Han Marinus and Bob van Hilten
6. The Movement Disorder Society Rating Scales Review Methodology, Anette Schrag
7. UPDRS and MDS-UPDRS, Christopher G. Goetz
8. Dyskinesia Rating Scales in Parkinson's Disease, Carlo Colossimo
9. Evaluation of motor complications: motor fluctuations, M. Merello and Angelo Antonini
10. Global Scales to Stage Disabilities in PD: The Hoehn and Yahr Scale, Werner Poewe
11. Quality of Life, Pablo Martinez-Martin
12. Measurements of Costs and Scales for Outcomes in Health Economic Studies of Parkinson's Disease, Richard Dodel
Part 3: Non-motor domains of Parkinson Disease
13. Anhedonia and Apathy, A Leentjens
14. Anxiety, Laura Marsh and AL Bush
15. Cognitive Impairment Screening Scales, Glenn Stebbins
16. Dysautonomia -Orthostatic hypotension, Le Traon et al
17. Fatigue, G Alves
18. Psychosis,H Fernandez
19. Depression. Anette Schrag
20. Nocturnal Sleep, Birgit Hogl


Cristina Sampaio, MD, PhD Instituto de Medicina Molecular Faculdade de Medicina de Lisboa Laboratorio de Farmacologia Clinica e Terapeutica, Lisboa, Portugal Christopher G. Goetz, MD Department of Neurological Sciences Rush University Medical Center Chicago, Illinois Anette Schrag, PhD, FRCP University Department of Clinical Neurosciences Institute of Neurology University College London London, UK