Pulmonary Arterial Hypertension

ISBN : 9780199572632

Michael A. Gatzoulis
192 Pages
131 x 196 mm
Pub date
Jul 2012
Oxford Cardiology Library
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This concise pocketbook provides an easily accessible resource on pulmonary arterial hypertension (PAH) for medical professionals (senior and trainees), nurses and allied disciplines. PAH is not any longer an orphan disease, nor is it associated with a grave prognosis and premature death (as it used to be the case a decade or two ago). Patients with PAH should enjoy improved survival and quality of life, provided that an early -and not late- diagnosis is made combined with timely initiation of advanced therapy in specialized/designated tertiary centres. This comprehensive text incorporates PAH expertise from the UK and the rest of the world. The book outlines the key points with respect to the latest classification, pathobiology, genetics, clinical assessment of the patient with suspected PAH and the role of imaging. There are specific chapters addressing different PAH aetiologies, namely idiopathic PAH, thromboembolic PAH, PAH related to connective tissue disease, congenital heart disease (Eisenmenger complex), respiratory disease and other unusual causes. Last, but not least, the book addresses counselling, contraception and the latest therapy for the challenging area of pregnancy and PAH, which is still associated with a high maternal mortality risk. The main objective of the book is to increase awareness of PAH, promote rapid diagnostic work up and timely specialist referral so that effective therapy is made available as early as possible to all patients with suspected or known PAH. Physicians -senior or Junior, nurse or other health care professional - whether senior or junior - who may encounter patients with PAH has much to gain from this book.


1. Classification of Pulmonary Arterial Hypertension and Current Therapeutic Approach
2. Pathobiology of Pulmonary Arterial Hypertension
3. Genetics
4. Clinical Assessment of the Patient with Suspected PAH and the Role of Cardiac Catheterization
5. Imaging of Pulmonary Arterial Hypertension
6. Idiopathic Pulmonary Arterial Hypertension
7. Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
8. Connective Tissue Disease Associated Pulmonary Arterial Hypertension
9. Eisenmenger Complex
10. Respiratory Causes of Pulmonary Hypertension
11. Other Causes of Pulmonary Hypertension
12. Pregnancy and Pulmonary Arterial Hypertension

About the author: 

Michael A. Gatzoulis, MD, PhD, is the Academic Head of the Adult Congenital Heart Centre and Centre for Pulmonary Arterial Hypertension at the Royal Brompton Hospital and the Professor of Cardiology, Congenital Heart Disease at the NHLI, Imperial College, London. Professor Gatzoulis has edited, co-edited or served as a Section Editor for several cardiology and other textbooks (including the reference text Diagnosis and Management of Adult Congenital Heart Disease and the Thorax Section of the 40th Edition of Gray's Anatomy) and authored over 200 peer-reviewed publications. He has been a Visiting Professor in a number of institutions worldwide, including Harvard, Stanford, Montreal Heart, the University of Athens and the Japanese Circulation Society, and served as President of the International Society for Adult Congenital Cardiac Disease, the largest relevant professional body in the world. His main interest is to promote the needs of CHD patients across the world and support education.

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