Oxford Specialist Handbook: Myeloproliferative Neoplasms

ISBN : 9780198744214

Tariq I. Mughal; Tiziano Barbui
352 Pages
100 x 180 mm
Pub date
Sep 2020
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Our understanding of myeloproliferative neoplasms (MPN) disorders, a group of clonal haematological malignancies characterized by excessive accumulation of one or more myeloid cell lineages, has grown considerably over the past four decades. Myeloproliferative Neoplasms offers a detailed evidence-based guide to MPNs in an easily accessible format, structured to facilitate learning specialist information by presenting core information in 'bite size' chunks. Each chapter summarises the state-of-the art preclinical and clinical knowledge, and its impact on the clinical management of patients with MPNs. This practical guide, written by experts in the field, is essential reading for oncologists, haematologists, and other health care professionals interested in the field of MPNs.


1 Tariq I. Mughal and Tiziano Barbui: History of the myeloproliferative neoplasms
2 Srinivas K. Tantravahi, Jamshid S. Khorashad, and Michael W.Deininger: Genomic landscape of myeloproliferative neo-plasms
3 Angela G. Fleischman and Richard A. Van Etten: Pathogenesis of myeloproliferative neoplasms
4 Hans Michael Kvasnicka and Juergen Thiele: Haematopathology of myeloproliferative neoplasms
5 Michele Baccarani, Fausto Castagnetti, Gabriele Gugliotta, Francesca Palandri, Simona Soverini, and Gianantonio Rosti: Prognostic factors of chronic myeloid leukaemia
6 Paola Guglielmelli and Alessandro M. Vannucchi: Molecular risk stratification of Myeloproliferative Neoplasms
7 Tariq I. Mughal: Chronic myeloid leukaemia
8 Tiziano Barbui and Guido Finazzi: Polycythaemia vera
9 Claire Harrison, Yan Beauverd, and Donal McLorran: Myelofibrosis
10 Carlos Besses, Beatriz Bellosillo, and Alberto Alvarez-Larran: Essential thrombocythemia
11 Jason Gotlib: Systemic mastocytosis
12 Eric Padron, David Sallman, Tariq I. Mughal, and Alan F. List: Myelodysplastic syndromes/myeloproliferative neoplasms
13 Andreas Reiter and Nicholas C. P. Cross: Eosinophilia-associated myeloproliferative neoplasms
14 Omar Abdelwahab, Raajit Rampal, Catriona Jamieson, and Tariq I. Mughal: Transformation of myeloproliferative neoplasms to acute leukaemia
15 Daniel Egan and Jerald P. Radich: Monitoring efforts in myeloproliferative neoplasms
16 Alessandro Rambaldi and Nicholas Kroger: Stem cell transplantation for BCR-ABL1-postive and negative myeloproliferative neoplasms
17 Holly L. Geyer, Deepti Radia, Nicholas Sarlis, and Ruben A. Mesa: Assessment of disease burden in patients with myeloproliferative neoplasms
18 Giovanni Barosi and Gianni Tognoni: Clinical trials in bcr-abl1-negative myeloproliferative neo-plasms

About the author: 

Following training in haematology/oncology and stem cell transplantation at Imperial College London, Professor Tariq I Mughal has held haematology/oncology leadership roles in cancer centres of excellence in London, Manchester and Denver. From an early stage in his career, he has been interested in precision haematologic cancer medicine and breast cancer. He now practices in Boston and London, and is a member of many learned societies. He is a professor of medicine and founder of Alpine Oncology Foundation dedicated to improve haematologic cancer care in economically challenged countries. He has published over 130 peer-reviewed scientific publications, 30 book chapters and authored/edited 13 books on cancers.; Following training inhematology/oncology in Padova, Professor Tiziano Barbui was appointed initially as a Professor, and later as the head of the department of Haematology at the (then) Ospedale Riuniti, and now Papa Giovanni XXIII, in Bergamo (Italy). He is a past-President of the Italian Society of Haematology, and chair of the Lupus Anticoagulant Subcommittee of the International Society of Thrombosis and Haemostasis. He currently leads the Italian GIMEMA group and is the co-chair of the European-Leukemia-Net working group on Myeloproliferative Disorders. He has published over 450 peer-reviewed scientific publications and authored/edited several books and chapters.

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