Foundations of Neural Development

ISBN : 9781605355795

S. Marc Breedlove
380 Pages
155 x 235 mm
Pub date
Feb 2017
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Foundations of Neural Development is a textbook written with a conversational writing style and topics appropriate for an undergraduate audience. Each chapter begins with a thought-provoking vignette, or a "real-life story," that the subsequent material illuminates. The "Researchers at Work" feature, available in every chapter, describes a classic study in detail, taking the reader through the hypothesis, test, result, and conclusion of an experiment. A marginal glossary, review questions, and bulleted summary are a few of the other features in the book. Chapters 1-7 unfold in the order of ontogeny, covering induction, the establishment of a body plan, neural migration, differentiation, axonal pathfinding, synapse formation, and apoptosis. Chapters 8-10 address activity-guided, experience-guided, and socially guided neural development--mechanisms that were crucial for the evolution of the human brain. Lively and engaging, with the finest illustrations, Foundations of Neural Development is the perfect book to help any undergraduate student understand how a single microscopic cell, a human zygote, can develop into the most complex machine on earth, the brain.


Prologue: The Rationalist Philosophers
1 The Metazoans' Dilemma: Cell Differentiation and Neural Induction
2 Coordinating Fates: Development of a Body Pattern
3 Upward Mobility: Neurogenesis and Migration
4 Seeking Identity: Neural Differentiation
5 Feeling One's Way: Axonal Pathfinding
6 Making Connections: Synapse Formation and Maturation
7 Accepting Mortality: Apoptosis
Interlude: The Empiricists Strike Back
8 Synaptic Plasticity: Activity-Guided Neural Development
9 Fine-Tuning Sensory Systems: Experience-Guided Neural Development
10 Maximizing Fitness: Socially Guided Neural Development
Epilogue: Immanuel Kant and the Critique of Pure Reason

About the author: 

S. Marc Breedlove, the Barnett Rosenberg Professor of Neuroscience at Michigan State University, has written over 130 scientific articles investigating the role of hormones in shaping the developing and adult nervous system, publishing in journals including Science, Nature, Nature Neuroscience, and the Proceedings of the National Academy of Science. He is also passionate about teaching--in the classroom, and in the greater community through interviews with the Washington Post, Los Angeles Times, New York Times, and Newsweek, as well as broadcast programs such as All Things Considered, Good Morning America, and Sixty Minutes. He has active grant support from the National Institute of Neurological Disorders and Stroke and the National Institute of Mental Health. Dr. Breedlove is a Fellow of the American Association for the Advancement of Science and the Association for Psychological Science.

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