ISBN : 9780198712558
Recent advances that allow scientists to quickly and accurately sequence a genome have revolutionized our view of the structure and function of genes as well as our understanding of evolution. A new era of genetics is underway, one that allows us to fully embrace Dobzhansky's famous statement that "Nothing in biology makes sense except in the light of evolution".
Genetics: Genes, Genomes, and Evolution presents the fundamental principles of genetics and molecular biology from an evolutionary perspective as informed by genome analysis.
By using what has been learned from the analyses of bacterial and eukaryotic genomes as its basis, the book unites evolution, genomics, and genetics in one narrative approach. Genomic analysis is inherently both molecular and evolutionary, and every chapter is approached from this unified perspective.
Similarly, genomic studies have provided a deeper appreciation of the profound relationships between all organisms - something reflected in the book's integrated discussion of bacterial and eukaryotic evolution, genetics and genomics. It is an approach that provides students with a uniquely flexible and contemporary view of genetics, genomics, and evolution.
1: Darwin's Finches: Evolution, Genomes, and Genes
2: The Central Dogma of Molecular Biology
3: Genome Structure, Organization, and Variation
4: Descent with Modification: DNA Replication and Mutation
5: The Inheritance of Single Gene Traits
6: The Cellular Basis for Mendelian Genetics
7: X-linked Genes and Sex Chromosomes
8: The Inheritance of Multiple Genes
9: The Locations of Genes on Chromosomes: Linkage and Genetic Maps
10: Human Genetic Mapping, Genome Wide Association Studies, and Complex Traits
11: Exchange and Evolution
12: Transcription: Reading and Expressing Genes
13: Translation: From Nucleic Acids to Amino Acids
14: Networks of Gene Regulation
15: Genetic Analysis of Cellular Processes
16: The Genetics of Populations
17: Metagenomes: Genome Analysis of Communities
"This is the book youve been looking for! A refreshing, new take on your classic genetics textbook. Its integrated approach successfully weaves basic and advanced topics, and leads students through the latest advances in the field." - André Antunes, Edge Hill University
"A very well written book, which is easy to read and which includes many interesting examples, figures and videos. It ties different fields of genetics and molecular biology into a coherent entity using an evolutionary perspective." - Anneli Hoikkala, University of Jyvaskylä
"An authoritative introductory genetics text which embeds all key concepts within their logical evolutionary framework." - Mike Jackson, Newcastle University
"There are many textbooks on genetics that take a purely molecular biology approach. It is good to have an evolutionary perspective on genetic knowledge." - Jan Hoole, Keele University
"I think that this book could be superior (to other textbooks) in linking the theory with the current knowledge of the genomic architectures of bacteria and eukaryotes and the state-of-the-art analytical approaches and technologies to address evolutionary questions." - Paolo Franchini, University of Konstanz
"Genetics text books can be rather dry. This one shows the relevance of genetics, molecular biology and evolution to modern life and also the impact of previous events (wonderfully explained) on humans today." - Judith Lock, University of Southampton
"A great textbook, easy to read (almost conversational writing style), excellent combination of text and colour figures. I would definitely recommend it. It is fresh and up to date, and the big advantage of this book is that it combines various disciplines at the undergraduate level, making for a strong cohesion in teaching." - Casper J. Breuker, Oxford Brookes University
"Meneely et al. use considerably teaching skills to capture the attnetion of students with a modest background in chemistry and biology. I particularly admire their attention to the three themes of their textbook. New topics incorporate what was learned in earlier chapters and students benefit in the review it provides and the integration of new knowledge it promotes. This is a volume that I hope will go through many editions." - Elof Axel Carlson in The Quarterly Review of Biology, Volume 93