Colorectal Cancer

ISBN : 9780199590209

Daniel Swinson; Matthew Seymour
144 Pages
131 x 196 mm
Pub date
Aug 2012
Oxford Oncology Library
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Colorectal cancer is one of the leading causes of cancer-related death in the world. Twenty-five percent of patients present with advanced disease and, despite complete surgical resection of early stage disease, 50% of patients relapse. The treatment of colorectal cancer has advanced rapidly in recent years, and controversies persist regarding optimal management (e.g. whether combination chemotherapy should be used first-line or in a staged fashion, how long to treat patients for and whether to use an intermittent or continuous schedule and whether to refer for a radical approach for advanced patients). Part of the Oxford Oncology Library, this pocketbook summarises the epidemiology and risk factors for developing colorectal cancer and the basic biology of the disease. The evidence governing approaches in diagnosis and oncological management both surgical and non-surgical of the primary tumour is also covered, including which surgical approaches to use and indications for neoaduvant / adjuvant radiotherapy and chemotherapy. Providing perspectives from the different disciplines involved including surgery, medical oncology, radiation oncology and palliative care, this pocketbook will serve as an invaluable reference for all health care professionals involved in the management of patients with colorectal cancer.


1. Introduction to colorectal cancer
2. Screening and diagnosis of colorectal cancer
3. Surgical management of colorectal cancer
4. Radiotherapy and rectal cancer
5. Pharmacology of anti-cancer drugs
6. Adjuvant chemotherapy
7. Systemic therapy for advanced colorectal cancer
8. Surgery for recurrent rectal and colonic cancer
9. Surgery for liver metastases
10. Surgery for pulmonary metastases
11. Colorectal cancer - surgical and non-surgical palliation
12. New therapeutic avenues in colorectal cancer

About the author: 

Dr. Daniel Swinson is Consultant Medical Oncologist and Honrary Senior Lecturer, Institute of Oncology, St. James's University Hospital, Leeds, UK; Prof. Matthew Seymour is Director of the National Cancer Research Network (NCRN), NCRN Coordinating Centre, University of Leeds, and Professor of Medicine, Institute of Oncology, St. James's University Hospital, Leeds, UK

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