The Developing Genome: An Introduction to Behavioral Epigenetics

ISBN : 9780199922345

David S. Moore
320 Pages
162 x 236 mm
Pub date
Apr 2015
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Why do we grow up to look, act, and feel as we do? Through most of the twentieth century, scientists and laypeople answered this question by referring to two factors alone: our experiences and our genes. But recent discoveries about how genes work have revealed a new way to understand the developmental origins of our characteristics. These discoveries have emerged from the new science of behavioral epigenetics-and just as the whole world has now heard of DNA, "epigenetics" will be a household word in the near future. Behavioral epigenetics is important because it explains how our experiences get under our skin and influence the activity of our genes. Because of breakthroughs in this field, we now know that the genes we're born with don't determine if we'll end up easily stressed, likely to fall ill with cancer, or possessed of a powerful intellect. Instead, what matters is what our genes do. And because research in behavioral epigenetics has shown that our experiences influence how our genes function, this work has changed how scientists think about nature, nurture, and human development. Diets, environmental toxins, parenting styles, and other environmental factors all influence genetic activity through epigenetic mechanisms; this discovery has the potential to alter how doctors treat diseases, and to change how mental health professionals treat conditions from schizophrenia to post-traumatic stress disorder. These advances could also force a reworking of the theory of evolution that dominated twentieth century biology, and even change how we think about human nature itself. In spite of how important this research is, behavioral epigenetics is still relatively unknown to non-biologists. The Developing Genome is an introduction to this exciting new discipline; it will allow readers without a background in biology to learn about this work and its revolutionary implications.


Part I: What's the Big Deal? Getting Up to Speed
1. Context
2. Phenotypes
3. Development
4. DNA
5. Zooming in on DNA
6. Regulation
7. Zooming in on Regulation
Part II: What Do We Know?
8. Epigenetics
9. Zooming in on Epigenetics
10. Experience
11. Zooming in on Experience
12. Primates
13. Memory
14. Zooming in on Memory
15. Nutrition
16. Zooming in on Nutrition
Part III: The Meanings and Mechanics of Inheritance
17. Inheritance
18. Multiplicity
19. Evidence
20. Grandparents
Part IV: Implications
21. Caution
22. Hope
23. Conclusions

About the author: 

David S. Moore is a professor of psychology at Pitzer College and Claremont Graduate University in southern California. He received his PhD in developmental and biological psychology from Harvard University. A developmental cognitive neuroscientist with expertise in infant cognition, his theoretical writings have explored the contributions of genetic, environmental, and epigenetic factors to human development. His book The Dependent Gene was widely adopted for use in undergraduate education and was nominated for the Cognitive Development Society's Best Authored Volume award.

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