Motor Neuron Disease in Adults

ISBN : 9780199783113

Mark B. Bromberg
368 Pages
184 x 257 mm
Pub date
Dec 2014
Contemporary Neurology Series
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Motor Neuron Disease in Adults reviews new information as it applies to all aspects of motor neuron disease (ALS, PLS, PMA). The choice of articles is for those that use evidence-based methods to ensure that the new information is solid and advances the topic or issue. The book can be used by anyone who provides any type of care to ALS patients. In particular, neurologists will find the latest information on diagnosis and management, as well as new information on genetics and frontotemporal lobe involvement. Allied health providers will find useful information for their discipline. Patients will also find both specific and general information to help understand what they are experiencing and how to help manage their symptoms.


Introduction to "Motor Neuron Disease"
1. History of the Recognition of Motor Neuron Disease
2. Nomenclature & Classification of Motor Neuron Disease
3. Clinical Anatomy, Physiology and Pathology of Motor Neuron Disease
4. Clinical Features of Motor Neuron Disease
5. Frontotemporal Dysfunction and Dementia in Amyotrophic Lateral Sclerosis
6. Laboratory Tests for Motor Neuron Disease
7. Biomarkers for Motor Neuron Disease
8. Imaging in Motor Neuron Disease
9. Diagnostic Criteria for Motor Neuron Disease
10. Differential Diagnosis of Motor Neuron Disease
11. Progression of Motor Neuron Disease
12. Epidemiology of Amyotrophic Lateral Sclerosis
13. Genetics of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia:
14. Genome-wide Screening to Identify ALS-associated Genes:
15. Pathology of ALS and Frontotemporal Lobar Degeneration:
16. Convergence and Divergence in ALS Syndrome: Genetics, Molecular Pathways and Molecular Mechanisms:
17. Immunologic Aspects of Amyotrophic Lateral Sclerosis:
18. Cyanobacteria, ALS, and the BMAA Hypothesis
19. Animal models of Adult Motor Neuron Disease
20. Multidisciplinary Clinics and Practice Parameters/Guidelines
21. Allied Health and Other Providers
22. Respiratory Assessment and Management
23. Nutritional Assessment and Management
24. Communication Assessment and Management
25. Psychological and Psychiatric Assessment and Management
26. Symptoms and Management
27. Intimacy, Sexuality and Pregnancy
28. Quality of Life
29. Caregiver Issues
30. End of Life Care
31. Costs of ALS Care:
32. Clinical Trial Designs in ALS:
33. Stem Cell Therapy for Motor Neuron Disease:

About the author: 

Marc B. Bromberg, MD, PhD Professor of Neurology University of Utah Salt Lake City, Utah.

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